White J, Streets AM. “Controller for microfluidic large-scale integration” bioRxiv (2017) DOI:

Chen T, Cao, C, Zhang J, Streets AM, Huang Y, Li T. “Stimulated Raman Scattering Micro-dissection Sequencing (SMD-Seq) for Morphology-specific Genomic Analysis of Oral Squamous Cell Carcinoma” bioRxiv (2017) DOI: 10.1101/121616

Wu AR†, Wang L†, Streets AM†, Huang Y†. “Single-Cell Transcriptional Analysis” Annual Review of Analytical Chemistry, Vol 10 (2017)



Cao C, Zhou D, Chen T, Streets AM†, Huang Y†. “Label-free digital quantification of lipid droplets in single cells by stimulated Raman microscopy on a microfluidic platform.” Analytical Chemistry, 88(9), 4931-4939  (2016) pdf



Streets AM, Huang Y. “How deep is enough in single-cell RNA-seq?” Nature Biotech, 32, 1005-1006 (2014)

Shen J, Jiang D, Fu Y, Wu X, Guo H, Feng B, Pang Y, Streets AM, Tang F, Huang Y. “H3K4me3 epigenomic landscape derived from ChIP-Seq of 1,000 mouse early embryonic cells.” Cell Research 25:143–147.

Streets AM, Li A, Chen T, Huang Y. “Imaging without fluorescence: Non-linear optical microscopy for quantitative cellular imaging.”  Analytical Chemistry, 96(17), p8506-8513, (2014)

Streets AM*, Zhang X*, Cao C, Pang Y, Wu X, Xiong L, Yang L, Fu Y, Zhao L, Tang F, and Huang Y. “Microfluidic single-cell whole-transcriptome sequencing.” Proceedings of the National Academy of Sciences, 111(19) 7048-7053 (2014) pdf

Streets AM, Huang Y. “Microfluidics for biological measurements with single-molecule resolution.” Current Opinion in Biotechnology, 25(1), 69-77 (2014)



Chen T, Lu F, Streets AM, Fei P, Quan J, Huang Y. “Optical imaging of non-fluorescent nanodiamonds in live cells using transient absorption microscopy.” Nanoscale, 5, 4701 (2013)

Streets AM, Huang Y. “Chip in a Lab: Microfluidics for next generation life science research.” Biomicrofluidics, 7 011302, (2013)

Streets AM, Sourigues Y, Kopito RR, Melki R, Quake SR. “Simultaneous measurement of amyloid fibril formation by dynamic light scattering and fluorescence reveal complex aggregation kinetics.” PLOS ONE, 8(1), e54541 (2013)



Kim SH*, Streets AM*, Lin RR, Quake SR, Weiss S, Majumdar DS. “High-throughput single-molecule optofluidic analysis.” Nature Methods, 8:3, 242-245 (2011)  pdf

-Highlighted in Physics Today ”Microfluidic devices streamline fluorescence experiments.” April (2011), p16-19

-Highlighted in Nature methods “News and Views: A triple threat to single molecules.” 8 213-215



Streets AM, Quake SR. “Ostwald ripening of clusters during protein    crystallization.” Physical Review Letters, 104, 178102 (2010) pdf


*contributed equally

†corresponding author

this link will direct you to Aaron’s publication list in google scholar